PUBLICATIONS 2026

Mitochondrial fission mediates an evolutionarily conserved antibacterial defense response

Kapetanovic, R. Afroz, S.F. Curson, J.E.B. Kirmes, I. Ramnath, D. Nothjunge, S. Liu, J. Atkinson, J.D. Ahier, A. Raven, K.D. Bosch, M. Keller, B. Lawrence, G.M.E.P. Gupta, K.D. Shakespear, M.R. Ferguson, C. Stocks, C.J. Bokil, N.J. Matthias, G. Nguyen, T.T.K. Khalil, Z.G. Reid, R.C. Hansford,K.

Sci Immunol 2026 11(118):eaed2623. doi: 10.1126/sciimmunol.aed2623. Epub 2026 Apr 24.

Restoration of Mucosa-Associated Invariant T-Cell Function in Healthcare-Associated Bacterial Infections Supports Recovery of Carbapenem Efficacy Against Resistant Bacteria Ex Vivo

Xue, Y. Karim, A.M. Sia, W.R. Han, F,.Chan, K.L. Chua, N.G. Hadadi, L. Liu, Z. Mak, J.Y.W. Fairlie, D.P. Wang, L-F. Sandberg ,J.K. Kwa , A.L-H. and Leeansyah, E.

J Infect Dis 2026 Apr 2:jiag151. doi: 10.1093/infdis/jiag151. Online ahead of print.

Specific targeting of MR1-antigen complexes using nanobodies

Hussain, M.H.S, Redmond, S.J. Awad, W. Xu, C. Soliman, C. Ciacchi, L. Gonzalez, A.P. Mak, J.Y.W. Fairlie, D.P. McCluskey,J. Uldrich, A.P. Rossjohn, J. Godfrey, D.I. Koay, H-F. Gherardin, N.A.

bioRxiv 2026 Mar 25:2026.03.22.713551. doi: 10.64898/2026.03.22.713551.

MAIT cell responses to S. aureus and sensitivity to HlgAB are modulated by activation and tissue-dependent virulence effects

Raineri, E.J.M. Boulouis, C. Mouchtaridi, E. Nilsén, V. Cai, C. Kammann, T. Tabusse, J. Sekine, T. Wild, N. Constantz, C. White, E. Müller, T.R. Marchalot, A. Ferreira, S. Kaushal, J. Mily, A. Franklin, M. Bonaiti, E. Eichhorn, M-L. Bassett, J. Stamper, C. Mak, J.Y.W. Fairlie, D.P.

bioRxiv 2026, Mar 19:2026.03.17.712383. doi: 10.64898/2026.03.17.712383.

The NF-κB transcription factor RelA directs mucosal-associated invariant T-cell development

Fulford, T.S. Koay, H-F. Grumont, R. Johnson, D.N. Scheer, S. Nel, H.J. Thomas, R. Mak, J.Y.W. Fairlie, D.P. Teh, C.E. Gray, D.H.D. Bryant, V.L. Zaph, C. O'Reilly, L.A. Gerondakis, S. and Godfrey, D.I.

Immunol Cell Biol 2026 104, 329-344.

Macrophage MR1 antigen presentation promotes MAIT cell immunity and lung microbiota modulation

Deng, J. Yan, Y. Zhang, X. Walsh, C.J. Montassier, E.,Sinha, D. Wang, H. Mousavizadeh, A. Ashayeripanah, M.Mak, J.Y. W., .Koay, H-F. Poch, T. Alexandre, Y.O. Mueller, S.N., .Vasanthakumar, A. Stinear, T.P. Jameson, V.J. Perez-Gonzalex, A. Kingham, J. Phan, T.G. Potemkin, N. Dryburgh, L. Schroeder, J. Fairlie, D.P. Mackay, L.K. Chen, Z. Cook, L. Hachani, A. Corbett, A.J. Roquilly, A. Villadnangos, J.A. McWilliam, H.E.G.

Science 2026, Jan 15;391(6782):eadr6322. doi: 10.1126/science.adr6322. Epub 2026 Jan 15.

Cytosolic delivery of bacterial metabolites by riboﬂavintransporters promotes MR1 antigen presentation and MAITcell recognition

Cruz-Gomez, S. Lim, H.J. Nijagal, B. Yang, Y. Lau, N. Mak, J.Y.W. Fairlie, D.P. Newton, H. Salio, M. Villadangos, J.A. & McWilliam, H.E.G.

Immunol Cell Biol 2026 104 329-344.

Experimental evidence for a metal-related function of a cyanobactin

Baur, P. Hill, T.A., Wu, K-C. Lim, J. Paterson, B.M. Velmururgan, G. Degnan, B.M. Fairlie, D.P. Comba, P.

Angew Chemie Int Ed 2026 e8567749.