FAIRLIE LAB
BIOCHEMISTRY
Biochemists in our group study enzymology, enzyme inhibition, protein chemistry, interactions between proteins and other proteins, RNA or DNA. We particularly use fluorescence and luminescence techniques, fluorescence polarization, isothermal calorimetry, thermal denaturation, NMR and CD and MD techniques, sedimentation equilibrium methods, TEM, confocal microscopy and live cell imaging. Biologists in our group interrogate human protein and cell function, and elucidate mechanisms of protein activation, biological/physiological processes, disease development, and drug action. Some researchers study rat or mouse models of human diseases. Researchers gain insights to human physiology or aberrant processes in disease, and develop interdisciplinary skills in enzymology, biochemistry, pharmacology, immunology, endocrinology, virology, parasitology, oncology and neurobiology.
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