PUBLICATIONS 2023

Molecular insights into metabolite antigen recognition by mucosal-associated invariant T cells.

Awad W, Ciacchi L, McCluskey J, Fairlie DP, Rossjohn J.Curr Opin Immunol. 2023 Aug;83:102351. doi: 10.1016/j.coi.2023.102351. Epub 2023 Jun 3.PMID: 37276819 Review.

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Histone deacetylase 7: a signalling hub controlling development, inflammation, metabolism and disease.

Wang Y, Abrol R, Mak JYW, Das Gupta K, Ramnath D, Karunakaran D, Fairlie DP, Sweet MJ.FEBS J. 2023 Jun;290(11):2805-2832. doi: 10.1111/febs.16437. Epub 2022 Mar 31.PMID: 35303381 Review.

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HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages.

Das Gupta K, Ramnath D, von Pein JB, Curson JEB, Wang Y, Abrol R, Kakkanat A, Moradi SV, Gunther KS, Murthy AMV, Stocks CJ, Kapetanovic R, Reid RC, Iyer A, Ilka ZC, Nauseef WM, Plan M, Luo L, Stow JL, Schroder K, Karunakaran D, Alexandrov K, Shakespear MR, Schembri MA, Fairlie DP, Sweet MJ.Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2212813120. doi: 10.1073/pnas.2212813120. Epub 2023 Jan 17.PMID: 36649417 Free PMC article.

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Suppression of MR1 by human cytomegalovirus inhibits MAIT cell activation.

Ashley CL, McSharry BP, McWilliam HEG, Stanton RJ, Fielding CA, Mathias RA, Fairlie DP, McCluskey J, Villadangos JA, Rossjohn J, Abendroth A, Slobedman B.Front Immunol. 2023 Feb 10;14:1107497. doi: 10.3389/fimmu.2023.1107497. eCollection 2023.PMID: 36845106 Free PMC article.

 

 

 

 

 

 

 

Ras-Related Protein Rab5a Regulates Complement C5a Receptor Trafficking, Chemotaxis, and Chemokine Secretion in Human Macrophages.

Wu KC, Condon ND, Hill TA, Reid RC, Fairlie DP, Lim J.J Innate Immun. 2023;15(1):468-484. doi: 10.1159/000530012. Epub 2023 Mar 7.PMID: 36882040 Free PMC article.

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N-(2-Aminophenyl)-benzamide Inhibitors of Class I HDAC Enzymes with Antiproliferative and Antifibrotic Activity.

Gerokonstantis DT, Mantzourani C, Gkikas D, Wu KC, Hoang HN, Triandafillidi I, Barbayianni I, Kanellopoulou P, Kokotos AC, Moutevelis-Minakakis P, Aidinis V, Politis PK, Fairlie DP, Kokotos G.J Med Chem. 2023 Oct 26;66(20):14357-14376. doi: 10.1021/acs.jmedchem.3c01422. Epub 2023 Oct 5.PMID: 37795958

 

 

 

 

 

 

 

Synthetic 5-amino-6-D-ribitylaminouracil paired with inflammatory stimuli facilitates MAIT cell expansion in vivo.

Nelson AG, Wang H, Dewar PM, Eddy EM, Li S, Lim XY, Patton T, Zhou Y, Pediongco TJ, Meehan LJ, Meehan BS, Mak JYW, Fairlie DP, Stent AW, Kjer-Nielsen L, McCluskey J, Eckle SBG, Corbett AJ, Souter MNT, Chen Z.Front Immunol. 2023 Aug 31;14:1109759. doi: 10.3389/fimmu.2023.1109759. eCollection 2023.PMID: 37720229 Free PMC article.

 

 

 

 

 

 

 

Protease-activated receptor 2 attenuates doxorubicin-induced apoptosis in colon cancer cells.

Shah H, Hill TA, Lim J, Fairlie DP.J Cell Commun Signal. 2023 Dec;17(4):1293-1307. doi: 10.1007/s12079-023-00791-6. Epub 2023 Nov 22.PMID: 37991681 Free PMC article.

 

 

 

 

 

 

 

Venom composition and bioactive RF-amide peptide toxins of the saddleback caterpillar, Acharia stimulea (Lepidoptera: Limacodidae).

Goudarzi MH, Eagles DA, Lim J, Biggs KA, Kotze AC, Ruffell AP, Fairlie DP, King GF, Walker AA.Biochem Pharmacol. 2023 Jul;213:115598. doi: 10.1016/j.bcp.2023.115598. Epub 2023 May 16.PMID: 37201876

 

 

 

 

 

 

 

Talarolides Revisited: Cyclic Heptapeptides from an Australian Marine Tunicate-Associated Fungus, Talaromyces sp. CMB-TU011.

Salim AA, Hussein WM, Dewapriya P, Hoang HN, Zhou Y, Samarasekera K, Khalil ZG, Fairlie DP, Capon RJ.Mar Drugs. 2023 Sep 11;21(9):487. doi: 10.3390/md21090487.PMID: 37755100 Free PMC article.

 

 

 

 

 

 

 

Wollamide Cyclic Hexapeptides Synergize with Established and New Tuberculosis Antibiotics in Targeting Mycobacterium tuberculosis.

Rollo RF, Mori G, Hill TA, Hillemann D, Niemann S, Homolka S, Fairlie DP, Blumenthal A.Microbiol Spectr. 2023 Aug 17;11(4):e0046523. doi: 10.1128/spectrum.00465-23. Epub 2023 Jun 8.PMID: 37289062 Free PMC article.

 

 

 

 

 

 

 

Effect of a protease-activated receptor-2 antagonist (GB88) on inflammation-related loss of alveolar bone in periodontal disease.

Francis N, Sanaei R, Ayodele BA, O'Brien-Simpson NM, Fairlie DP, Wijeyewickrema LC, Pike RN, Mackie EJ, Pagel CN.J Periodontal Res. 2023 Jun;58(3):544-552. doi: 10.1111/jre.13120. Epub 2023 Mar 31.PMID: 37002616

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